cellcyclecheckpoint

由 R Visconti 著作 · 2016 · 被引用 336 次 — MK-1775, by abrogating the G2/M checkpoint, allows cells with damaged DNA to progress into mitosis, leading to mitotic catastrophe. Thus, most ...

2022年7月30日 — A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be ...

The key role of checkpoint proteins is to detect DNA damage and send a signal to delay cell cycle advance until the damaged chromosomes are repaired (Figure 1).

由 M Molinari 著作 · 2000 · 被引用 460 次 — Checkpoints are mechanisms that regulate progression through the cell cycle insuring that each step takes place only once and in the right sequence.

The mitotic spindle checkpoint occurs at the point in metaphase where all the chromosomes should/have aligned at the mitotic plate and be under bipolar tension.

A checkpoint is a stage in the eukaryotic cell cycle at which the cell examines internal and external cues and decides whether or not to move forward with ...

由 KJ Barnum 著作 · 2014 · 被引用 713 次 — Cell cycle checkpoints are surveillance mechanisms that monitor the order, integrity, and fidelity of the major events of the cell cycle.

A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be halted until ...

This checkpoint's primary responsibility is to make sure that each of the chromosomes has already been duplicated and that the replicated DNA has not been ...

This checkpoint takes place during the M phase. It is also called the spindle checkpoint because the cell examines whether all sister chromatids are correctly ...